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Rita Anjos1; Luisa Vieira1; Mariana Cardoso2; Ana Xavier3; Cristina Ferreira3; Cristina Brito3


1- Serviço de Oftalmologia, Centro Hospitalar de Lisboa Central, EPE, Lisboa
2- Serviço de Oftalmologia, Centro Hospitalar do Baixo Vouga
3- Unidade de Oftalmologia, Hospital de Dona Estefânia, Centro Hospitalar de Lisboa Central, EPE, Lisboa

-  56º Congresso Sociedade Portuguesa de Oftalmologia, Vilamoura, dezembro 2013, Vilamoura, dezembro 2013
-  40th Annual Meeting of the European Pediatric Ophthalmological Society (EPOS), Barcelona, novembro 2014
-  14th Meeting European Schoolfor Advanced Studies in Ophthalmology (ESASO) Retina Academy, Istambul, novembro 2014


Introduction: Primary congenital glaucoma (PCG) is a relatively rare disease but an important cause of blindness. Although admittedly related to an abnormality in the development of the iridocorneal angle, its pathophysiology is not fully defined. The purpose of our study is to evaluate the choroidal thickness (CT) in children with primary congenital glaucoma (PCG) and healthy children.

Methods or Study Design: Prospective study of children with PCG (glaucoma group) and healthy children. With resource of optical coherence tomography the following measures were made: retinal thickness (RT) and CT at the fovea, 1.5 mm nasal and 1.5 mm temporal to the fovea; peripapillary retinal nerve fiber layer thickness (RNFL) and CT. Results: Data from 12 eyes of 9 children with PCG and 17 eyes of 9 healthy children were analyzed. Macular CT and RT and peripapillary CT were similar in both groups (p  > 0.05). However, when patients with high ametropias were excluded, foveal CT was higher in the glaucoma group (p < 0.05). There was a correlation between foveal CT and global RNFL in the glaucoma group (r = 0.764; p = 0.01) and in the control group (r = 0.570; p = 0.042).

Conclusions: Although numerous studies have been recently published on the choroidal changes in adult glaucoma, the subject is still controversial. In our study there were no global differences between CT in children with or without PCG. Keywords: Primary Congenital Glaucoma, Choroidal Thickness, Retinal Thickness, Retinal Nerve Fiber Layer, Visual Acuities