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2018

ANUÁRIO DO HOSPITAL DONA ESTEFÂNIA
REPOSITÓRIO MÉDICO CIENTÍFICO

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PEDIATRIC HERPETIC EYE INFECTION - DIAGNOSIS AND TREATMENT

Guilherme Néri Pires, Joana Cardigos, Ana Paixão, Margarida Marques, Alcina Toscano

Serviço de Oftalmologia, Centro Hospitalar de Lisboa Central

- European Society of Ophthalmology 2017, Barcelona, 10-13 junho de 2017
- Electronic Poster Presentation

Purpose: Herpes simplex type 1 virus (HSV-1) is present in 50-90% of the world population and is the leading cause of blindness world-wide. Compared to the adult population, the paediatric one, has a higher incidence of stromal disease, with higher recurrence rate and greater refractive errors risk, which can lead to amblyopia. An early diagnosis and effective therapy is therefore mandatory;
Method: We present a retrospective study of the clinical results of 13 children, being the age of on-set, sex, initial symptom, time for diagnosis, treatment and final best corrected visual acuity (BCVA) reported. Diagnosis was made with clinical criteria. All statistical analysis was made through Microsoft Excel.
Results: Average age of disease on-set was 5,2 years and the average time of follow-up 8,5 months. Average time for diagnosis was 11 days. The most common clinical manifestation was unilateral palpebral disease (8/13), 4 of which later showed associated epithelial keratitis. The other patients, 2 presented with isolated epithelial keratitis and 3 stromal keratitis. Disease recurrence was greater in the topical treatment monotherapy (3/5) than in the combined therapy group (1/8). 12 of the 13 patients obtained a BCVA higher than 20/40, being the average 0.82;
Conclusion: Paediatric herpetic ocular infection is a major diagnosis and therapeutic challenge. Amblyopia risk entails a severe visual prognosis being of the outermost importance a correct therapy and adequate follow-up of this patients.

Palavras-chave: Herpetic Keratitis, Children