1- Serviço de Imunoalergologia, Hospital de Dona Estefânia, Centro Hospitalar de Lisboa Central, EPE
2- CEDOC, NOVA Medical School / Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Portugal
- European Respiratory Society International Congress 2017, 9-13 September, Milan, Italy
- Apresentação sob a forma de poster; publicação de resumo
- Reunião Internacional
Background: In preschool wheezing children, the use of Impulse oscillometry (IOS), a passive technique that needs lower cooperation then spirometry, may improve the identification of airway obstruction and the responsiveness to treatment. In the literature, there are few data about reliability of the IOS measurements in this children group.
Aim: To assess the IOS measurements variability in pre-school recurrent wheezing children.
Methods: Children sequentially evaluated in our lung laboratory, aged between 4 to 6 years old, who underwent IOS (Jaeger) were invited to carry out two series of measurements, performed 15 minutes apart without any intervention. We selected the Resistance at 5Hz (R5) as outcome variable. The Bland-Altman plot was used to analyze the agreement between measurements. For assessment of within-occasion variability, the coefficient of repeatability (CR) and the coefficient of variation (CV) intermeasurement and the average CV intra-measurement were applied (ATS 2007 recommendation).
Results: Twenty children were evaluated (75% boys) with a mean age of 4.8 years (standard-deviation (SD: 0.9 years). Regarding R5, the mean difference between the two series of measurements was 5.7% (± 1.96 SD: -8.2% to 19.5%). In the within-occasion, the CR and the CV intermeasurement were 12.6% and 7.6%, respectively. The average CV of the intra-measurements was 5.4%.
Conclusions: It was found variability for R5 measurements, which should be considered when assessing the bronchial response to bronchodilators or bronchoconstrictors. These results seem to be useful for a better monitoring of the lung function in preschool children using IOS.
Palavras Chave: preschool, wheezing, lung function, IOS